Chiral Symmetry Breaking in a Soft-Wall Model of AdS/QCD

We incorporate chiral symmetry breaking in a soft-wall version of the AdS/QCD model by using a modified dilaton profile and a quartic term in the bulk scalar potential. This allows one to separate the dependence on spontaneous and explicit chiral symmetry breaking. The resulting mass spectra in the scalar, vector and axial-vector sectors compares favorably with the respective QCD resonances.Comment: Proceedings of "Crossing the Boundaries: Gauge Dynamics at Strong Coupling", Minneapolis, 2009. 12 pages, 7 figure

Weaving Entities into Relations: From Page Retrieval to Relation Mining on the Web

With its sheer amount of information, the Web is clearly an important frontier for data mining. While Web mining must start with content on the Web, there is no effective ``search-based'' mechanism to help sifting through the information on the Web. Our goal is to provide a such online search-based facility for supporting query primitives, upon which Web mining applications can be built. As a first step, this paper aims at entity-relation discovery, or E-R discovery, as a useful function-- to weave scattered entities on the Web into coherent relations. To begin with, as our proposal, we formalize the concept of E-R discovery. Further, to realize E-R discovery, as our main thesis, we abstract tuple ranking-- the essential challenge of E-R discovery-- as pattern-based cooccurrence analysis. Finally, as our key insight, we observe that such relation mining shares the same core functions as traditional page-retrieval systems, which enables us to build the new E-R discovery upon today's search engines, almost for free. We report our system prototype and testbed, WISDM-ER, with real Web corpus. Our case studies have demonstrated a high promise, achieving 83%-91% accuracy for real benchmark queries-- and thus the real possibilities of enabling ad-hoc Web mining tasks with online E-R discovery

What Can the Organization of the Brain’s Default Mode Network Tell us About Self-Knowledge?

Understanding ourselves has been a fundamental topic for psychologists and philosophers alike. In this paper we review the evidence linking specific brain structures to self-reflection. The brain regions most associated with self-reflection are the posterior cingulate and medial prefrontal (mPFC) cortices, together known as the cortical midline structures (CMSs). We review evidence arguing that self-reflection is special in memory, while noting that these brain regions are often engaged when we think about others in our social worlds. Based on the CMSs’ patterns of connectivity and activity, we speculate about three possible interpretations of their role in supporting self-reflection that are somewhat overlapping, and not intended to be mutually exclusive. First, self may be a powerful, but ordinary case for a cognitive system specialized for thinking about people. Second, mPFC may serve as a processing “hub,” binding together information from all sensory modalities with internally generated information. Third, mPFC may serve as a cortical director of thought, helping to guide moment-by-moment conscious processing. Suggestions are made for future research avenues aimed at testing such possibilities

The seafloor revealed: The geology of the northwestern Gulf of Maine inner continental shelf

Maine Geological Survey, Open-File Report 96-6. Explains the surficial geology, physiography, and geologic history of the Maine coast. Methods and analysis detail how the seafloor was studied. Data were interpreted from side-scan sonar records, seismic reflection profiles, bottom samples, and submersible dives.https://digitalmaine.com/mgs_publications/1118/thumbnail.jp

Surficial geology of the Maine inner continental shelf; Mt. Desert Island to Jonesport, Maine

Maine Geological Survey, Geologic Map 96-12https://digitalmaine.com/mgs_maps/1217/thumbnail.jp

Volume and quality of sand and gravel aggregate in the submerged paleodeltas of the Kennebec and Penobscot River mouth areas, Maine

Maine Geological Survey, Open-File Report 97-5. Reports on results of a geophysical and coring investigation of sand volumes at mouths of Kennebec and Penobscot Rivershttps://digitalmaine.com/mgs_publications/1117/thumbnail.jp

Infrared Observations of the Helix Planetary Nebula

We have mapped the Helix (NGC 7293) planetary nebula (PN) with the IRAC instrument on the Spitzer Space Telescope. The Helix is one of the closest bright PNs and therefore provides an opportunity to resolve the small-scale structure in the nebula. The emission from this PN in the 5.8 and 8 μm IRAC bands is dominated by the pure rotational lines of molecular hydrogen, with a smaller contribution from forbidden line emission such as [Ar III] in the ionized region. The IRAC images resolve the "cometary knots," which have been previously studied in this PN. The "tails" of the knots and the radial rays extending into the outer regions of the PN are seen in emission in the IRAC bands. IRS spectra on the main ring and the emission in the IRAC bands are consistent with shock-excited H_2 models, with a small (~10%) component from photodissociation regions. In the northeast arc, the H_2 emission is located in a shell outside the Hα emission

CHO microRNA engineering is growing up : recent successes and future challenges

microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of Chinese Hamster Ovary cells. However, until recently, research was limited by a lack of genomic sequence information on this industrially important cell line. With the publication of the genomic sequence and other relevant data sets for CHO cells since 2011, the doors have been opened for an improved understanding of CHO cell physiology and for the development of the necessary tools for novel engineering strategies. In the present review we discuss both knowledge on the regulatory mechanisms of microRNAs obtained from other biological models and proof of concepts already performed on CHO cells, thus providing an outlook of potential applications of microRNA engineering in production cell lines